A Phase I Study of iPS Cell Generation From Patients With COPD
This trial is active, not recruiting.
|Conditions||thoracic diseases, respiratory tract diseases, cancer of lung, cancer of the lung, lung cancer, lung diseases, obstructive, copd, pulmonary emphysema, neoplasms, lung, neoplasms, pulmonary, pulmonary cancer, pulmonary neoplasms, carcinoma, non-small-cell lung, carcinoma, small cell|
|Start date||September 2009|
|End date||January 2017|
|Trial size||50 participants|
|Trial identifier||NCT01860898, 09-005334|
As part of the long-term goal of successfully implementing tissue regeneration strategies in an individualized manner for patients with thoracic diseases including, but not limited to: cystic fibrosis, pulmonary fibrosis and pulmonary hypertension, the investigators will assess the feasibility of collecting skin biopsies from patients undergoing surgery for thoracic disease, culturing skin fibroblasts from the biopsy, and reprogramming these skin fibroblasts into induced pluripotent cells.
|Intervention model||single group assignment|
|Primary purpose||basic science|
time frame: 1 year
Male or female participants at least 18 years old.
Inclusion Criteria: - Undergoing Thoracic Surgery at the Mayo Clinic Rochester - Presence of a Thoracic Disease
|Official title||A Phase I Study of iPS Cell Generation From Patients With COPD|
|Principal investigator||Dennis A Wigle, MD, PhD|
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