This trial is active, not recruiting.

Conditions affective disorders, anxiety disorders, attention deficit disorder, substance abuse
Treatments cognitive remediation, computer skills training
Sponsor New York State Psychiatric Institute
Collaborator National Institute of Mental Health (NIMH)
Start date July 2012
End date December 2015
Trial size 188 participants
Trial identifier NCT01815398, #6586, 1R21MH092569-01A1


Many young people who are homeless have cognitive deficits which impede their ability to secure and maintain employment. This study looks to see if targeting cognitive deficits can improve cognition and vocational outcome.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose treatment
(Active Comparator)
26 sessions conducted 2-3 times a week to train in computer skills related to the workforce.
computer skills training
Participants utilize an interactive software program that delivers tutorials, lessons, and practice sessions to develop computer skills for office based employment. During the learning activities, the clinician offers coaching and assistance in setting up computerized training exercises as needed.
26 sessions conducted 2-3 times a week of cognitive remediation
cognitive remediation NEAR
Neuropsychological Educational Approach to Remediation (NEAR) is an evidence based, manualized cognitive remediation program that targets cognitive deficits (eg memory, processing speed, executive functioning, working memory and attention) with the intent of improving daily functioning.NEAR is conducted in a small group setting, allowing for supportive social interaction while participants work at their own computer station on engaging computerized activities that are selected to address their unique profile of cognitive deficits. Then, as a group they discuss how their respective cognitive activities will help them achieve their vocational goals.

Primary Outcomes

Global Cognition Score
time frame: Baseline, 13, 26 sessions

Secondary Outcomes

Vocational outcome
time frame: Baseline, 13, 26 sessions

Eligibility Criteria

Male or female participants from 18 years up to 22 years old.

Inclusion Criteria: - have a current Diagnostic and Statistical Manual (DSM-IV) Axis I diagnosis - residing at Covenant House New York Rights of Passage Program - psychiatrically stable for at least 21 days - English speaking Exclusion Criteria: - mental retardation (<70 Intelligence Quotient; IQ) on premorbid intelligence estimate) - risk for suicide or violence - unremitted substance dependence within the past 6 weeks

Additional Information

Official title Cognitive Skills Training to Improve Vocational Outcome in Homeless Youth
Principal investigator Alice A Medalia, PhD
Description The aim of this research is to conduct a controlled study of cognitive remediation, to provide feasibility data on adapting an established empirically-based cognitive intervention for homeless youth to help them attain vocational goals. The ultimate purpose is that youth will improve in cognitive functioning and have better functional outcomes including jobs to sustain independent living. The results of this study will inform a larger trial on the efficacy of cognitive remediation in homeless youth to improve cognition and vocational outcomes. Hypotheses are that, compared to those in an active control group receiving computerized work-skills training, individuals who receive cognitive remediation will show greater cognitive benefits on proximal measures of neurocognition and evidence better vocational outcome as defined by greater number of hours worked. This study will address the service gap in the use of integrated psychosocial interventions for homeless populations as the first investigation of cognitive remediation in homeless youth.
Trial information was received from ClinicalTrials.gov and was last updated in October 2016.
Information provided to ClinicalTrials.gov by New York State Psychiatric Institute.