This trial is active, not recruiting.

Condition function of mitomycin c in cornea
Treatment mitomycin c
Sponsor Far Eastern Memorial Hospital
Start date August 2012
End date July 2013
Trial size 5 participants
Trial identifier NCT01808495, FEMH-IRB-101002-F, NSC101-2320-B-418-002


The purpose of this study is to investigate the role of nuclear Fibulin-1 (FBLN1) in Human Corneal Fibroblasts under treatment of mitomycin C (MMC).

United States No locations recruiting
Other countries No locations recruiting

Study Design

Time perspective prospective

Primary Outcomes

Modification of nuclear Fibulin-1 accumulation in suppressing gene expression
time frame: 3 days post mitomycin C treatment

Eligibility Criteria

Male or female participants at least 20 years old.

Inclusion Criteria: - The frozen storage cells in liquid nitrogen were amplified from the residual corneal rim of the donors with more than 20 years old following penetrating keratoplasty. Exclusion Criteria: - The donors were younger than 20 years old.

Additional Information

Principal investigator Tsan-Chi Chen, PhD
Trial information was received from ClinicalTrials.gov and was last updated in August 2015.
Information provided to ClinicalTrials.gov by Far Eastern Memorial Hospital.