Function and Modulation of Fibulin-1 Assembly in Nucleus of Corneal Fibroblasts
This trial is active, not recruiting.
|Condition||function of mitomycin c in cornea|
|Sponsor||Far Eastern Memorial Hospital|
|Start date||August 2012|
|End date||July 2013|
|Trial size||5 participants|
|Trial identifier||NCT01808495, FEMH-IRB-101002-F, NSC101-2320-B-418-002|
The purpose of this study is to investigate the role of nuclear Fibulin-1 (FBLN1) in Human Corneal Fibroblasts under treatment of mitomycin C (MMC).
Modification of nuclear Fibulin-1 accumulation in suppressing gene expression
time frame: 3 days post mitomycin C treatment
Male or female participants at least 20 years old.
Inclusion Criteria: - The frozen storage cells in liquid nitrogen were amplified from the residual corneal rim of the donors with more than 20 years old following penetrating keratoplasty. Exclusion Criteria: - The donors were younger than 20 years old.
|Principal investigator||Tsan-Chi Chen, PhD|
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