This trial is active, not recruiting.

Conditions chromosomal aneuploidies, single gene desease
Treatment blastocoele aspiration
Sponsor Cervesi Hospital, Cattolica, Italy
Start date January 2013
End date December 2016
Trial size 35 participants
Trial identifier NCT01780415, NewEra21972


The objective will focus on the characterization of DNA fragments present in Blastocoele fluid, and the evaluation of these fragments as potential target for Preimplantation Genetic Diagnosis. To reach this goal, real-time PCR, Whole Genome Amplification techniques and -subsequently- Next Generation Sequencing and aCGH approaches will be used.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model cohort
all the patients that have supernumerary embryos to vitrify at blastocyst stage
blastocoele aspiration

Primary Outcomes

Number of samples with DNA in blastocoele Fluid
time frame: 6 month

Secondary Outcomes

Number of euploid samples
time frame: 8 months

Eligibility Criteria

Female participants from 18 years up to 40 years old.

Inclusion Criteria: - IVF patient with supernumerary embryos to vitrify at blastocyst stage Exclusion Criteria: - IVF patient without blastocyst formation

Trial information was received from ClinicalTrials.gov and was last updated in July 2016.
Information provided to ClinicalTrials.gov by Cervesi Hospital, Cattolica, Italy.