Genomic DNA in Human Blastocoele Fluid
This trial is active, not recruiting.
|Conditions||chromosomal aneuploidies, single gene desease|
|Sponsor||Cervesi Hospital, Cattolica, Italy|
|Start date||January 2013|
|End date||December 2016|
|Trial size||35 participants|
|Trial identifier||NCT01780415, NewEra21972|
The objective will focus on the characterization of DNA fragments present in Blastocoele fluid, and the evaluation of these fragments as potential target for Preimplantation Genetic Diagnosis. To reach this goal, real-time PCR, Whole Genome Amplification techniques and -subsequently- Next Generation Sequencing and aCGH approaches will be used.
all the patients that have supernumerary embryos to vitrify at blastocyst stage
Number of samples with DNA in blastocoele Fluid
time frame: 6 month
Number of euploid samples
time frame: 8 months
Female participants from 18 years up to 40 years old.
- IVF patient with supernumerary embryos to vitrify at blastocyst stage
- IVF patient without blastocyst formation
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