This trial is active, not recruiting.

Conditions amd, glaucoma
Treatment optical coherence tomography
Sponsor Centre Hospitalier Universitaire Dijon
Start date October 2009
End date October 2013
Trial size 3000 participants
Trial identifier NCT01766596, Creuzot-Garcher PHRC IR 2009


The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies.

The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
optical coherence tomography

Primary Outcomes

Measure the mean thickness of postganglionic fibers
time frame: T=7 years of the 3C cohort

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - Persons who have given their written consent - Persons who are taking part in the Dijon 3C study Exclusion Criteria: - Persons who are not registered with social security agency - Persons who are unable to sit upright during a consultation

Additional Information

Official title Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging
Trial information was received from ClinicalTrials.gov and was last updated in August 2016.
Information provided to ClinicalTrials.gov by Centre Hospitalier Universitaire Dijon.