Overview

This trial is active, not recruiting.

Conditions brachial plexus anesthesia, analgesia
Treatment supraclavicular brachial plexus block
Sponsor University Hospital Dubrava
Start date October 2012
End date January 2013
Trial size 55 participants
Trial identifier NCT01739270, 0911

Summary

Adding dexamethasone to local anesthetic will significantly prolong duration of brachial plexus anesthesia and analgesia.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking single blind (investigator)
Primary purpose treatment
Arm
(Active Comparator)
25ml 0.5% levobupivacaine plus 4mg Dexamethasone are given for supraclavicular brachial plexus block for upper extremity surgery
supraclavicular brachial plexus block
(Active Comparator)
25ml 0.5% levobupivacaine plus 1ml 0.9% saline are given for supraclavicular brachial plexus block for upper extremity surgery
supraclavicular brachial plexus block

Primary Outcomes

Measure
duration of analgesia
time frame: 24 hour postoperatively

Secondary Outcomes

Measure
postoperative analgesic consumption
time frame: 24 hour

Eligibility Criteria

Male or female participants from 18 years up to 80 years old.

Inclusion Criteria: - patients aged 18 years or older - ASA (American Society of Anesthesiologists) physical status I, II or III Exclusion Criteria: - refusal of the patients to give informed consent - preexisting coagulation disorders - local infection at the site of the block - neuropathy - drug or alcohol abusers - known allergy to the drug used in study - operation time exceeding six hours

Additional Information

Official title Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia After Supraclavicular Brachial Plexus Blockade
Description Operations of upper extremities are often performed in regional anesthesia blocks. Single-injection blocks are effective, but time limited. Adding 4mg of dexamethasone to 0.5% levobupivacaine will significantly prolong duration of brachial plexus anesthesia and analgesia for fracture operations of upper extremity. This effect will result in less opioid use postoperatively.
Trial information was received from ClinicalTrials.gov and was last updated in July 2015.
Information provided to ClinicalTrials.gov by University Hospital Dubrava.