This trial is active, not recruiting.

Conditions alzheimer´s disease, general anesthesia
Sponsor University Hospital, Linkoeping
Start date May 2012
End date July 2016
Trial size 877 participants
Trial identifier NCT01695889, DEMA-1


The purpose of this study is to compare exposure to general anesthesia between cases with a diagnosis of Alzheimer´s disease and controls without diagnosis, through studies of medical records. The investigators wish to explore if there is a relationship between exposure to general anesthesia and the development of Alzheimer´s disease.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case control
Time perspective retrospective

Primary Outcomes

Exposure to general anesthesia
time frame: Up to 20 years in retrospect

Secondary Outcomes

Exposure to inhaled anesthetics
time frame: Up to 20 years in retrospect

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - Clinical diagnosis of Alzheimer´s disease - Previous exposure to anesthesia Exclusion Criteria: - Inability to retrieve medical records

Additional Information

Official title A Case-control Study of Exposure to General Anesthesia and a Diagnosis of Alzheimer´s Disease Later in Life.
Trial information was received from ClinicalTrials.gov and was last updated in March 2016.
Information provided to ClinicalTrials.gov by University Hospital, Linkoeping.