This trial is active, not recruiting.

Condition healthy subjects
Treatment caffeine
Phase phase 4
Sponsor Hospital do Servidor Publico Estadual
Start date January 2012
End date October 2012
Trial size 25 participants
Trial identifier NCT01693809, 0127/11


The principal aim of this study is to evaluate the presence of changes in cervical vestibular evoked myogenic potentials (VEMPc) after acute intake of caffeine in healthy subjects.

Secondarily, it wants to standardize normal values ​​exam VEMPc in otorhinolaryngology service of the hospital.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Endpoint classification pharmacodynamics study
Intervention model single group assignment
Masking single blind (investigator)
Primary purpose screening
Caffeine 420mg, one time

Primary Outcomes

Alteration of p13 and n23 latency and p13-n23 amplitude before and after caffeine intake.
time frame: 60 minutes

Eligibility Criteria

Male or female participants from 20 years up to 40 years old.

Inclusion Criteria: - healthy subjects Exclusion Criteria: - hearing impairment - caffeine abuse 24 hours before the test - medication remains - hypertension, dyslipidemia, diabetes mellitus or sleep disorders.

Additional Information

Official title The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy
Principal investigator Ana Maria Almeida Sousa, MD
Trial information was received from ClinicalTrials.gov and was last updated in September 2012.
Information provided to ClinicalTrials.gov by Hospital do Servidor Publico Estadual.