Diet and Hereditary Haemorrhagic Telangiectasia
This trial is active, not recruiting.
|Condition||hereditary haemorrhagic telangiectasia (hht)|
|Treatments||questionnaire on dietary history, questionnaire on nosebleed severity, one week food diary generated by weighing foods, blood tests for full blood count, albumin, and indices of nutritional status|
|Sponsor||Imperial College London|
|Start date||April 2011|
|End date||September 2013|
|Trial size||150 participants|
|Trial identifier||NCT01692015, CLS21|
Hereditary Haemorrhagic Telangiectasia (HHT) affects 1 in 5,000 people. The purpose of this study is to provide data regarding the diet and nosebleed frequency using a questionnaire.
This will be filled in by people with HHT.
The questionnaire has been designed in paper format.
|Intervention model||single group assignment|
|Primary purpose||supportive care|
Dietary food item content
time frame: 1 year
time frame: 3 months
Male or female participants at least 18 years old.
Inclusion Criteria: - A diagnosis of hereditary Haemorrhagic Telangiectasia (HHT) Exclusion Criteria: - Unable to provide informed consent - Presence of another major organ disorder that may affect nutritional status, such as inflammatory bowel disease, or celiac disease.
|Official title||A Questionnaire Study on Diet and Hereditary Haemorrhagic Telangiectasia|
|Principal investigator||Claire L Shovlin, PhD FRCP|
|Description||Hereditary Haemorrhagic Telangiectasia (HHT) affects 1 in 5,000 people, usually causing nosebleeds, skin blood spots, and/or anaemia as a result of bleeding from the nose or gut. The majority of people with HHT also have abnormal blood vessels (arteriovenous malformations) in internal organs such as the lungs, liver and brain. Management of this multisystem disorder is highly challenging. The Lead Applicant has spent 20 years working on this rare disease, and identified multiple areas where more evidence is required to assist clinicians and patients with this lifelong condition. A particular issue is whether the diet influences HHT or its complications in any way. In this study, people will fill in two questionnaires, one giving details of their diet, and another details of their nosebleeds. They will also be asked to consider participating in an accessory study arm which includes weighing food for one week and providing a food diary, in addition to having a single set of blood test.|
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