Overview

This trial is active, not recruiting.

Conditions identify the presence of a marker of ischemia/hypoperfusion of the brain via peripheral blood, ischemia/hypoperfusion of brain
Sponsor Virginia Commonwealth University
Start date March 2011
End date August 2018
Trial size 10 participants
Trial identifier NCT01639534, HM12941

Summary

The purpose of the study is to determine if a new blood test can help the doctor determine if there is brain injury or ischemia. Ischemia occurs when not enough oxygen gets to the brain. In this study the investigators are analyzing your blood for a new test that might help doctors decide if symptoms are from a neurologic problem.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case-only
Arm
Subjects requiring Carotid Stenting Procedure at Virginia Commonwealth University/Mcv Health Systems

Primary Outcomes

Measure
Biomarkers of Ischemia: Levels of Xanthine, Hypoxanthine and Inosine during Carotid Stenting Procedures
time frame: analysis will occur after all samples collected

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Men and Women over age of 18 non - Women who are not pregnant - Subject who are not prisoners - Subjects presenting to the operation room for a Carotid artery stenting procedure - Hemoglobin greater than or equal to 11mg/dl - Subjects who speak english - Subjects 18 years of age or older Exclusion Criteria: - Hemoglobin less than 11mg/dl - Women who are pregnant - Children under age of 18 - Prisoners - Non English

Additional Information

Official title Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures
Principal investigator Lynne Gehr, MD
Description We will compare a new blood test with routine tests that the doctor will order as part of your normal care. This study will measure new biomarkers (biomarker is a specific distinguishing feature used to measure or indicate the effects or progress of a disease or condition) of neurologic stress called xanthine, hypoxanthine, and inosine. Blood will be drawn as a part of the study to measure these biomarker levels in your blood. This blood will be analyzed i the laboratory at VCU and possibly at a future date at another institution. No names will be associated with the blood sample
Trial information was received from ClinicalTrials.gov and was last updated in June 2016.
Information provided to ClinicalTrials.gov by Virginia Commonwealth University.