Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures
This trial is active, not recruiting.
|Conditions||identify the presence of a marker of ischemia/hypoperfusion of the brain via peripheral blood, ischemia/hypoperfusion of brain|
|Sponsor||Virginia Commonwealth University|
|Start date||March 2011|
|End date||August 2018|
|Trial size||10 participants|
|Trial identifier||NCT01639534, HM12941|
The purpose of the study is to determine if a new blood test can help the doctor determine if there is brain injury or ischemia. Ischemia occurs when not enough oxygen gets to the brain. In this study the investigators are analyzing your blood for a new test that might help doctors decide if symptoms are from a neurologic problem.
Subjects requiring Carotid Stenting Procedure at Virginia Commonwealth University/Mcv Health Systems
Biomarkers of Ischemia: Levels of Xanthine, Hypoxanthine and Inosine during Carotid Stenting Procedures
time frame: analysis will occur after all samples collected
Male or female participants at least 18 years old.
Inclusion Criteria: - Men and Women over age of 18 non - Women who are not pregnant - Subject who are not prisoners - Subjects presenting to the operation room for a Carotid artery stenting procedure - Hemoglobin greater than or equal to 11mg/dl - Subjects who speak english - Subjects 18 years of age or older Exclusion Criteria: - Hemoglobin less than 11mg/dl - Women who are pregnant - Children under age of 18 - Prisoners - Non English
|Official title||Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures|
|Principal investigator||Lynne Gehr, MD|
|Description||We will compare a new blood test with routine tests that the doctor will order as part of your normal care. This study will measure new biomarkers (biomarker is a specific distinguishing feature used to measure or indicate the effects or progress of a disease or condition) of neurologic stress called xanthine, hypoxanthine, and inosine. Blood will be drawn as a part of the study to measure these biomarker levels in your blood. This blood will be analyzed i the laboratory at VCU and possibly at a future date at another institution. No names will be associated with the blood sample|
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