This trial is active, not recruiting.

Condition colon cancer
Treatment 18f-fluordeoxyglucose positron emission tomography/ computed tomography
Sponsor Naestved Hospital
Collaborator University of Copenhagen
Start date July 2009
End date March 2013
Trial size 66 participants
Trial identifier NCT01636674, SJ-82


The investigators are investigating the usefulness of 18F-Fluordeoxyglucose Positron Emission Tomography/ Computed Tomography (18F-FDG PET/CT) for staging and follow-up of colon cancer. Furthermore, the investigators combine 18F-FDG PET findings with clinical and histopathological features, circulating tumor cell (CTC) analyses, tumor gene expression and measurements of circulating cancer biomarkers sUPAR, TIMP-1 and CEA in order to predict tumor recurrence.

The investigators hypothesis: The combination of functional imaging by 18F-FDG PET/CT and pre-existing and evolving molecular biomarkers will optimize tumor characterization, staging of disease and early detection of recurrence.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
Primary purpose diagnostic

Primary Outcomes

time to recurrence
time frame:

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - clinical or histological diagnosis of malignant clonic neoplasm (distance of more than 15 cm from anal ring) - 18 years of age or older - written informed consent Exclusion Criteria: - diabetes - known malignant disease other than colon cancer - known metastatic disease - impairment of renal function - allergy to CT contrast agents - body weight of more than 150 kg - claustrophobia

Additional Information

Official title Value of 18F-Fluordeoxyglucose Positron Emission Tomography/ Computed Tomography and Molecular Tumor Characterisation in Preoperative Staging og Postoperative Control of Colon Cancer
Principal investigator Bodil E Engelmann, MD
Trial information was received from ClinicalTrials.gov and was last updated in July 2012.
Information provided to ClinicalTrials.gov by Naestved Hospital.