Effect OF Nitrous Oxide On Acute Pain and Opioid Consumption, and Chronic Pain After Hysterectomy
This trial is active, not recruiting.
|Conditions||abdominal hysterectomy (& wertheim), nitrous oxide, general anesthesia|
|Treatments||nitrous oxide, general anesthesia with oxygen|
|Sponsor||The Cleveland Clinic|
|Start date||May 2012|
|End date||December 2017|
|Trial size||200 participants|
|Trial identifier||NCT01622335, 1491-952|
The study is prospective and double blind. In the clinic, patients undergoing hysterectomy that meet the criteria for inclusion into the study and agreed to participate in the study will be randomized into two groups.
|Intervention model||parallel assignment|
|Primary purpose||supportive care|
|Masking||participant, investigator, outcomes assessor|
Nitrous oxide and chronic pain
time frame: 30 days post operative
Nitrous oxide and opioid consumption
time frame: 4 hours post operative
Female participants from 18 years up to 65 years old.
Inclusion Criteria: - 18 to 65 years old at time of the first procedure - Female - American Society of Anesthesiologists physical status I or II - Hysterectomy undergoing the general anesthesia Exclusion Criteria: - Neuropathic disease - Chronic opioid users - Contraindication for Nitrous Oxide receive - Consent will not be obtained patient - Psychiatric disorders - Current or recent drug abuse (within past 6 months).
|Official title||Effect OF Nitrous Oxide On Acute Pain and Opioid Consumption, and Chronic|
|Principal investigator||Alparslan Turan, M.D.|
|Description||The study is prospective and double blind. In the clinic, patients undergoing hysterectomy that meet the criteria for inclusion into the study and agreed to participate in the study will be randomized into two groups. In the first group of patients will receive Nitrous Oxide and In the second group of patients will receive oxygen during the general anesthesia.|
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