Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
This trial is active, not recruiting.
|Sponsor||University of Leipzig|
|Collaborator||German Research Foundation|
|Start date||April 2007|
|Trial size||200 participants|
|Trial identifier||NCT01605123, KFO152/SFB1052-C5|
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age.
To identify these alterations and risk factors, the investigators have established a cohort of 177 healthy obese and lean control children, age ranging from 6y to 18y, for evaluation of cardiovascular and metabolic parameters, as well as quantification of biomarkers of obesity and inflammation. Follow-up analyses are planned after 2 years (completed) and additionally after 5, 7 and 9 years.
In addition, the investigators will assess the effects of increased physical activity and exercise on cardiovascular function.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Observational model||case control|
time frame: 7 years
Male or female participants from 6 years up to 25 years old.
Inclusion Criteria: - height -2 to +2 SDS - pubertal stage adequate for age - no medications - written consent of guardians and children≥12y - weight ≥ -2 SDS Exclusion Criteria: - secondary/syndromal obesity - known existing hypertension - chronic disease (eg. errors of metabolism) - acute illness (eg. respiratory tract infection) - previous hypertensive or antidiabetic treatment- weight loss attempts 6 weeks prior to assessment
|Official title||Leipzig Artherobesity Childhood Cohort|
|Principal investigator||Antje Körner, MD|
Call for more information