This trial is active, not recruiting.

Condition mastication disorder
Treatments autologous platlet rich fibrin, one side in control group
Phase phase 4
Sponsor Majid Eshghpour
Start date December 2011
End date April 2012
Trial size 30 participants
Trial identifier NCT01583491, 900093


The purpose of this study is to determine the influence of platelet rich fibrin to reduction of periodontal problems after surgical removal of third molar.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking double blind (investigator, outcomes assessor)
Primary purpose prevention
(Active Comparator)
prf insert into surgical site immediate after surgery
autologous platlet rich fibrin prf
one dose immediate after surgery
(Placebo Comparator)
one side in control group
control group insert any things after surgery

Primary Outcomes

Measurement of periodontal pocket depth at mid buccal, disto buccal and distolingual of mandibular second molar
time frame: 4 months

Eligibility Criteria

Male or female participants from 18 years up to 35 years old.

Inclusion Criteria: - have 2 impacted third molars Exclusion Criteria: - periodontal disease - history of periodontal surgery

Additional Information

Official title Evaluation of Platelet Rich Fibrin Efficacy on Reduction of Periodontal Problems
Description After extraction or surgical removal of third molar, a deep bony pocket created behind the second molar specially in the mandible. For reduction of this problem, investigators, needed to acceleration tissue healing. For this purpose, investigators used platelet rich fibrin (autologous) and followed patient for 3 months.
Trial information was received from ClinicalTrials.gov and was last updated in April 2012.
Information provided to ClinicalTrials.gov by Mashhad University of Medical Sciences.