Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure
This trial is active, not recruiting.
|Condition||acute and chronic hepatic failure with developing coma|
|Sponsor||The University of Texas Medical Branch, Galveston|
|Start date||February 2012|
|End date||December 2015|
|Trial size||20 participants|
|Trial identifier||NCT01582087, 12-030|
The purpose of this study is to understand mechanisms associated with the development of coma during hepatic failure. As of today, those mechanisms are not understood and it is difficult to intervene and prevent coma development which is often associated with mortality. Understanding the mechanism involved, may allow us to prevent coma and develop new therapies to treat this disease.
All patients presenting at University of Texas Medical Branch (UTMB) with acute and chronic hepatic failure and who are developing coma
The relationship that exist between a liver undergoing chronic or acute degeneration and hepatic coma.
time frame: 8 weeks
Male or female participants at least 18 years old.
- Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics for chronic or acute hepatic failure will be included in the study.
- Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics that do not have a diagnosis of chronic or acute hepatic failure
|Official title||Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure|
|Principal investigator||Luca Cicalese, MD|
Call for more information