This trial is active, not recruiting.

Condition coxarthrosis
Treatments direct lateral approach in total hip arthroplasty, anterior approach
Phase phase 4
Sponsor Sorlandet Hospital HF
Start date January 2012
End date December 2016
Trial size 120 participants
Trial identifier NCT01578746, 2011/2581 D, 811398


In total hip arthroplasty several approaches can be used. The newly introduced minimally invasive anterior approach is supposed to cause less damage to tendons and muscles. At the same time there are reports that there are more complications when this approach is used. The direct lateral approach is the most used in Norway and is well documented. There are however those who postulate that there is to high risk of damage to the gluteus medius causing Trendelenburg gait. In the investigators hospital both the anterior and direct lateral approach is used with good result. The investigators main study hypothesis is that there is no difference between the use of anterior or direct lateral approach i total hip arthroplasty in regards to postoperative function and pain, complications, radiological finds (X-ray and MRI), markers for muscle damage (i.e CK-total) or other clinical outcomes.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking single blind (subject)
Primary purpose treatment
(Active Comparator)
Patient operated using direct lateral approach.
direct lateral approach in total hip arthroplasty Hardinge approach
The use of direct lateral approach in total hip arthroplasty
(Active Comparator)
Patient operated using anterior approach.
anterior approach Smith-Petersen approach
The use of anterior approach in total hip arthroplasty

Primary Outcomes

Change in function
time frame: 2 years

Secondary Outcomes

Muscle damage
time frame: Day of operation and next four consecutive days
time frame: First four postoperative days
X-ray assessment
time frame: 3 and 12 months
time frame: 3 and 12 months

Eligibility Criteria

Male or female participants from 20 years up to 80 years old.

Inclusion Criteria: - Clinical and radiological diagnosis of coxarthrosis Exclusion Criteria: - Previous surgery on affected hip - No mental disability preventing follow-up

Additional Information

Official title Comparison Between Minimally Invasive Anterior Approach and Direct Lateral Approach in Total Hip Arthroplasty - A Prospective Randomized Trial
Principal investigator Svein Andreas Svenningsen, M.D, Ph.D
Trial information was received from ClinicalTrials.gov and was last updated in June 2013.
Information provided to ClinicalTrials.gov by Sorlandet Hospital HF.