Sleep and Cerebral Responses to High Altitude
This trial is active, not recruiting.
|Conditions||acute mountain sickness, high altitude pulmonary edema, high altitude cerebral edema|
|Sponsor||University Hospital, Grenoble|
|Start date||July 2011|
|End date||October 2011|
|Trial size||12 participants|
|Trial identifier||NCT01565603, RCB 2011-A00071-40|
Mechanisms underlying high-altitude intolerance as well as exercise performance limitation in hypoxia still remain to be fully understood. Recent data suggest that sleep disturbances on one hand and cerebral perturbations on teh other hand may be key mechanisms. The investigators evaluated 12 healthy subjects at sea level and at 4400 m of altitude for 7 days in order to better describe sleep and cerebral responses. The investigators hypothesized that sleep and cerebral disturbances play a critical role for the developement of acute mountain sickness and for exercise performance limitation during acute high-altitude exposure.
Male participants from 18 years up to 50 years old.
Inclusion Criteria: - 18 to 50 yrs old - Male Exclusion Criteria: - Respiratory, cardiac, metabolic or neuromuscular diseases - History of severe acute mountain sickness
|Official title||Intolerance Mechanisms and Exercise Performance Limitation During a High Altitude Stay: Investigation of Sleep and Cerebral Responses|
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