This trial is active, not recruiting.

Condition adaptation reaction
Treatment physical training
Sponsor University of Copenhagen
Start date March 2011
End date June 2012
Trial size 41 participants
Trial identifier NCT01530035, H-1-2011-013


A one-year intervention study of 41 healthy elderly men aged 65-75-years.Of these, 24 subjects are untrained men with no regular training activity for the last 5 years. After medical screening and pre-testing, they will be randomized into a football group (n=9), a strength-training group (n=9) or a sedentary control group (n=6). Additional 17 subjects are recruited from local football clubs and have been active football players for the last 40 years. Training will be performed 3x1 hour per week and evaluation will take place after 0, 3 and 12 months. Primary endpoints will be changes in cardiac and vascular structure and function measured by advanced echocardiography (tissue Doppler and speckle tracking imaging), and peripheral arterial tonometry (Endo--‐PAT device). Secondary endpoints will be evaluation of potential changes in VO2 max, blood pressure, muscle capillaries, lipid profile, circulating catecholamines, body composition, and insulin resistance.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose prevention
(Active Comparator)
physical training
physical training
(No Intervention)
elderly men with no change in daily activities
(No Intervention)
veteran soccer players with a 40 year history of continues soccer playing

Primary Outcomes

cardiac adaptations
time frame: after 16 weeks and one year

Secondary Outcomes

Cardiorespiratory fitness, muscular adaptations, Bloodpressure and Glucose tolerance
time frame: after 16 weeks and one year

Eligibility Criteria

Male participants from 65 years up to 75 years old.

Inclusion Criteria: - 65-75 year old men - healthy - non-smoking - non-hypertension - non- cardiac disease Exclusion Criteria: - smoking - cardiac disease - biomechanical disorders - cardiac medication

Additional Information

Official title Cardiovascular and Muscular Adaptations to Recreational Soccer and Strength Training in Elderly Healthy 65-75-year-old Men
Trial information was received from ClinicalTrials.gov and was last updated in February 2012.
Information provided to ClinicalTrials.gov by University of Copenhagen.