This trial is active, not recruiting.

Conditions statin therapy, adherence
Treatment cpatch intervention to support statin adherence
Sponsor University of Saskatchewan
Collaborator Saskatchewan Ministry of Health
Start date March 2010
End date November 2011
Trial size 2250 participants
Trial identifier NCT01509014, NCT00971412


Despite proven benefits in reducing morbidity and mortality, many patients become nonadherent to statin therapy within the first year of starting. Due to their accessibility and frequent patient contact, pharmacists are well-positioned to improve medication adherence.

The purpose of this study is to determine whether a simple intervention by community pharmacists can improve statin adherence in new statin users.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking open label
Primary purpose health services research
All patients receiving statins from pharmacies allocated to the pharmacist intervention arm of the study
cpatch intervention to support statin adherence
Routine identification of new statin users (first year of therapy), consistent assessment of barriers to adherence at every dispensation for these patients, reassurance about efficacy and safety, and proactive response to identified adherence barriers.
(No Intervention)
Pharmacies not allocated to the intervention arm will serve as the control. They received no training on the CPATCH intervention and provide usual care to patients at their pharmacy.

Primary Outcomes

Mean statin adherence among all eligible new users of statin medications with at least 6 months of follow-up from index prescription
time frame: 6 months

Secondary Outcomes

Proportion of new statin users with adherence greater than or equal to 80%
time frame: 6 months
Persistence with statin use among patients with a minimum of 12 months of follow-up
time frame: 6 months

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - Pharmacies must fill at least 85 statin prescriptions in a six-week period - CPATCH intervention was given priority over other study initiatives offered by the pharmacy - All members of pharmacy staff provided informed consent

Trial information was received from ClinicalTrials.gov and was last updated in January 2012.
Information provided to ClinicalTrials.gov by University of Saskatchewan.