Overview

This trial is active, not recruiting.

Condition cognitive benefits
Treatment citicoline, omega-3 fatty acids and creatine
Sponsor Deborah Yurgelun-Todd
Start date February 2012
End date March 2017
Trial size 25 participants
Trial identifier NCT01502813, IRB_48136

Summary

The purpose of this study is to determine the functional effects of a citicoline, creatine, and omega-3 fatty acids combination when administered for a duration of four weeks (28 days) to non-psychiatric adult female participants.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Intervention model single group assignment
Masking open label
Primary purpose treatment
Arm
(Experimental)
citicoline, omega-3 fatty acids and creatine CDP-Citicoline
Citicoline: 500 mg/day for 28 days Omega-3 Fatty Acids: 2 g/day for 28 days Creatine: 5 g/day for 28 days

Primary Outcomes

Measure
Change from Baseline in Neuropsychological Tests that measure attention and memory at 14 days
time frame: Baseline and 14 days from baseline
Change from Baseline in Neuropsychological Tests that measure attention and memory at 28 days
time frame: Baseline and 28 days from baseline

Eligibility Criteria

Female participants from 40 years up to 60 years old.

Inclusion Criteria: - Female - Age 40-60 years Exclusion Criteria: - Significant medical condition - History of co-morbid psychiatric disorders - Current Axis I or II diagnosis - Past participation in a pharmacotherapeutic trial - Head injury with LOC>5 minutes - Use of psychotropic medication - History of fish allergies - Medical condition associated with clinically significant decreases in coagulability - Use of anticoagulant medication

Additional Information

Principal investigator Deborah Yurgelun-Todd, PhD
Description Standard clinical measures for mood and neuropsychological measures of attention, cognitive inhibition and memory will be applied before, during, and after a course of a daily supplementation of citicoline, creatine and omega-3 for 28 days to non-psychiatric adult female participants. We hypothesis that the combination of supplements will improve memory and attention in healthy adult women.
Trial information was received from ClinicalTrials.gov and was last updated in November 2016.
Information provided to ClinicalTrials.gov by University of Utah.