Stanford's Outcomes Research in Kids
This trial is active, not recruiting.
|Condition||bacterial, viral and other infectious agents|
|Treatment||removal of triclosan-containing cleaning products from household.|
|Start date||March 2010|
|End date||June 2017|
|Trial size||200 participants|
|Trial identifier||NCT01442701, 17756|
The investigators intend to investigate whether the rise in childhood obesity is caused by the loss of recurrent and chronic infections in modern, industrialized society, beginning in utero and extending through early childhood. The investigators will also examine whether the antimicrobial triclosan, present in numerous cleaning and hygiene products, decreases the incidence of infection within a household.
Height-for-weight Z scores
time frame: Age 3 years
time frame: In utero to 3 years of age
Female participants at least 18 years old.
Inclusion Criteria: Subjects must meet all of the following inclusion criteria to participate in the study: 1. Able to provide written informed consent. 2. Able to communicate effectively in verbal English or Spanish. 3. Willing to provide blood, saliva, urine and stool specimens from herself, and willing to provide blood, saliva, urine and stool specimens from her infant. 4. Willing to provide consent for review of Primary Provider Medical Records regarding, for the mother, medical history and infectious and other conditions during pregnancy, and for the infant, Apgar scores, height and weight measurements at birth and over time, infectious and other disease diagnoses and treatment, and vaccination records. Exclusion Criteria: 1. More than one fetus. 2. High risk pregnancy. 3. Intent to move from the Bay Area within three years after enrollment. 4. History of diagnosis and/or treatment, and any current diagnosis or treatment, of type 1 diabetes or of major mental illness. 5. History of diagnosis and/or treatment, and any current diagnosis or treatment, of a thyroid disorder or other endocrine condition. 6. History of diagnosis and/or treatment, and any current diagnosis or treatment that has resulted in severe immunosuppression. 7. A household member who has a compromised immune system 8. Other conditions that in the opinion of the PI would make the subject an unacceptable candidate for this study.
|Official title||Stanford's Outcomes Research in Kids (STORK)|
|Principal investigator||Catherine Ley, PhD|
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