This trial is active, not recruiting.

Condition obesity
Sponsor Huashan Hospital
Start date December 2009
End date December 2013
Trial size 200 participants
Trial identifier NCT01387438, KY2009-279


Previous studies have shown that active brown adipose tissue (BAT) is present in adults and may play important roles in material and energy metabolism. However, most of these studies were tumor-based populations and retrospective study. Due to the large amount in our cohort, the investigators are able to promote a cross-sectional study of the incidence and factors of BAT in adult chinese. In addition, the investigators can analyse the metabolic profiles in healthy adults with active BAT.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case control
Time perspective cross-sectional

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Subjects with detectable brown adipose tissue - Negative controls,consisting of one subject who underwent PET/CT scans at the same day but without detectable BAT Exclusion Criteria: - Younger than 18 years - Pregnant women - With implantable medical electronic instrument

Additional Information

Official title Cross-sectional Study on the Incidence,Factors,and Importance of Brown Adipose Tissue in Adult Chinese
Description The investigators will perform a cross sectional analysis on the chinese adults who use 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) to scan the whole body at Huashan Hospital from 2009 to 2013. BAT activity will be measured by PET/CT. Not only demographic data on sex, age, medication and medical history,but also data on body composition and physical examination will be collected for all subjects. Imaging date,outdoor temperature and fasting blood samples will be collected as well. In addition, the investigators will analyse the metabolic profiles in healthy adults with active BAT and their negative controls,such as lipid profiles,fasting glucose and insulin sensitivity, adipokines and other biochemical markers.
Trial information was received from ClinicalTrials.gov and was last updated in July 2011.
Information provided to ClinicalTrials.gov by Huashan Hospital.