The Incidence and Factors of Brown Adipose Tissue in Chinese
This trial is active, not recruiting.
|Start date||February 2010|
|End date||December 2011|
|Trial size||600 participants|
|Trial identifier||NCT01381042, KY2009-307|
Previous studies have shown active brown adipose tissue (BAT) is present in adults and may play important roles in regulating energy homeostasis. However, the majorities of these studies were done in patients undergoing scanning for cancer surveillance, and may not reflect BAT behavior in healthy individuals. In addition, little is known about the ethnic variation in BAT activity, particularly in Chinese adults. Due to the large amount in our cohort, we are able to look at the difference between subjects for cancer surveillance (CS) and subjects for medical check-up (MC), and to clarify the impact of clinical and lifestyle parameters.
Male or female participants at least 18 years old.
Inclusion Criteria: - Subjects with detectable brown adipose tissue - Negative controls, consisting of two subjects who underwent PET/CT scans at the same day but without detectable BAT Exclusion Criteria: - Younger than 18 years
|Official title||Retrospective Study on the Incidence and Factors of Brown Adipose Tissue in Adult Chinese|
|Description||We will study scanning database including data from July 2006 to June 2010 in Shanghai. BAT activity will be measured via 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT). Age, imaging date, sex, and outdoor temperature will be collected for all patients. To evaluate the effects of multiple metabolic parameters on BAT activity, we will collect height, body weight, fasting plasma glucose (FPG), medical history, diagnosis, smoking, alcohol consumption, exercise, liver triglyceride content, and thyroid metabolic activity for all patients with detectable BAT and their negative controls, consisting of two patients who underwent PET/CT scans at the same day but without detectable BAT.|
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