MI Mortality Risk and Between-hospital Risk Variation in the United Kingdom and Sweden
This trial is active, not recruiting.
|Condition||acute myocardial infarction|
|Sponsor||University College, London|
|Collaborator||NICOR/MINAP, the United Kingdom|
|Start date||March 2011|
|End date||December 2014|
|Trial size||370000 participants|
|Trial identifier||NCT01359033, FP7-EIS-WP7-MINAP|
The study aims to investigate the differences in survival trajectories and hospital variability in myocardial infarction (MI) mortality rates in the UK and Sweden.
|United States||No locations recruiting|
|Other countries||No locations recruiting|
time frame: 30-day
time frame: 1 year
Male or female participants at least 30 years old.
Inclusion Criteria: - Patients aged above 30 years old who had hospital admission for acute myocardial infarction. - Admission period ranged from 1st January, 2004 to 31th December, 2008. Exclusion Criteria: - Patients with missing data in the admission time and/or primary outcomes.
|Official title||Compare the Patient Risk and Between-hospital Variation in Myocardial Infarction Mortality in the United Kingdom and Sweden|
|Principal investigator||Sheng-Chia Chung, Ph.D|
|Description||Limited evidence is available in comparing hospital level care and reference mortality risks between countries, due to the scarce availability of nationwide coronary heart disease data. The demographics and medical expenditure percentage are comparable in the United Kingdom and Sweden; however, the in-hospital case-fatality rates within 30 days after admission for acute myocardial infarction was greater in the UK than Sweden (6.3% versus 2.9%)(OECD, 2009). To investigate the discrepancy, the current study aims to compare the mortality risk differences and associated explanatory factors between the two countries. Results of the study can contribute to myocardial infarction care implementation in the UK and Sweden. The UK Myocardial Ischaemia National Audit Project (MINAP)and Register of Information and Knowledge about Swedish Heart Intensive care Admissions (RIKS-HIA) are few quality national registries currently available for acute coronary syndrome. Using data from the MINAP and RIKS-HIA, we propose to investigate (1)the survival trajectories for a reference patient with myocardial infarction and (2) hospital variability in myocardial infarction mortality rate in the UK and Sweden, adjusted for important patient-level and hospital-level covariates.|
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