Overview

This trial is active, not recruiting.

Condition obsessive compulsive disorder
Treatments internet-based cognitive behavior therapy, support therapy on internet
Phase phase 2
Sponsor Karolinska Institutet
Start date February 2011
End date June 2011
Trial size 101 participants
Trial identifier NCT01347099, OCD-S

Summary

Cognitive behavior therapy (CBT) is an effective treatment for obsessive compulsive disorder (OCD) but there is a lack of properly trained CBT therapists. One possible treatment alternative is Internet-based CBT (ICBT) with minimal therapist input. The aim of this study was therefore to evaluate ICBT for OCD.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose treatment
Arm
(Experimental)
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks.
internet-based cognitive behavior therapy
Internet-delivered CBT. Contact with therapist thru an e-mail system. 10 weeks
(Placebo Comparator)
10 weeks. Therapist support contact through e-mail.
support therapy on internet
Internet-delivered support therapy. Contact with therapist thru an e-mail system. 10 weeks

Primary Outcomes

Measure
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.
time frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended

Secondary Outcomes

Measure
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.
time frame: Two days before treatment, once per week for 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Change from Baseline of obsessions and compulsions after 10 weeks and at 3- and 12 months after treatment.
time frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after the treatment has ended
Change from Baseline of depressive symptoms after 10 weeks and at 3- and 12 months after treatment.
time frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Change from Baseline of meta cognitions after 10 weeks and at 3- and 12 months after treatment.
time frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended
Change from Baseline of quality of life after 10 weeks and at 3- and 12 months after treatment.
time frame: Two weeks before treatment, 10 weeks after treatment starts, 3 and 12 months after treatment has ended

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Primary diagnosis of obsessive compulsive disorder (OCD) - At least 18 years old - Able to read and write in swedish - Computer access Exclusion Criteria: - other primary diagnosis - substance abuse, - psychosis, - bipolar disorder, - suicidal ideation, - adjusted pharmacological treatment the last two months - current psychological treatment for OCD, - been treated with CBT the last two years, - serious somatic disease, - Y--‐BOCS>31 - hoarding as primary OCD subtype

Additional Information

Official title Internet-based Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Randomized Controlled Trial
Principal investigator Christian Rück, MD, PhD
Description This is a randomized controlled trial with 101 participants. The control group receives support therapy on demand on the Internet.
Trial information was received from ClinicalTrials.gov and was last updated in May 2011.
Information provided to ClinicalTrials.gov by Karolinska Institutet.