This trial is active, not recruiting.

Conditions joint pain, stiffness
Sponsor Brigham and Women's Hospital
Start date January 2010
End date January 2013
Trial size 200 participants
Trial identifier NCT01341314, ArthFndtn


Research has shown that early aggressive use of medicines may stop rheumatoid arthritis (RA)or slow its damage. The key to this is to find people with early symptoms which could be RA and have them get a diagnosis, treatment and follow-up.

This study will recruit persons who've gone to the internet looking for information about their symptoms. After answering a screening survey, the person with possible symptoms will be linked to the study website for a more detailed symptom questionnaire.

After completing that questionnaire the person will receive information about the second part of the study which includes an examination with a rheumatologist (arthritis doctor)and laboratory tests.

Based on the joint examination and laboratory tests, the rheumatologist will tell the person the likelihood of having RA, and make recommendations and if needed a referral for care and treatment. Treatment is not a part of this study.

This study will also compare the information on the subject's questionnaires to the doctor's joint examination and the laboratory tests with the hope of developing a simple inexpensive case finding questionnaire.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Joint pain or swelling for less than 3 months - Be able to use the internet Exclusion Criteria: - Non English speaking - Diagnosis of rheumatoid arthritis

Additional Information

Official title Proof of Concept of an Internet-based Series Design Case-finding System for Very Early Rheumatoid Arthritis.
Trial information was received from ClinicalTrials.gov and was last updated in May 2012.
Information provided to ClinicalTrials.gov by Brigham and Women's Hospital.