Overview

This trial is active, not recruiting.

Conditions gestational diabetes, type 2 diabetes
Sponsor Laval University
Start date September 2009
End date September 2012
Trial size 450 participants
Trial identifier NCT01340924, GDM

Summary

The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective

Primary Outcomes

Measure
Glucose tolerance assessed using a 75g-Oral Glucose Tolerance Test (OGTT)
time frame: 1 year

Secondary Outcomes

Measure
overweight/obesity
time frame: 1 year
abdominal obesity
time frame: 1 year
inflammatory state
time frame: 1 year
metabolic syndrome
time frame: 1 year

Eligibility Criteria

Female participants at least 18 years old.

Inclusion Criteria: - Women aged ≥18 years with a diagnosis of GDM in the past 5 years based on the diagnosis data available from the RAMQ databanks. Exclusion Criteria: - Pregnant women, women with type 1 diabetes.

Additional Information

Official title Key Determinants of Type 2 Diabetes Prevention Among Women With a History of Gestational Diabetes Mellitus
Principal investigator Julie Robitaille, R.D., Ph.D.
Description Type 2 diabetes (T2D) is a growing public health problem owing to its prevalence as well as its high morbidity and mortality rates. The identification of high-risk populations is of great importance particularly because the onset of T2D can be prevented or delayed by lifestyle modifications. Among high-risk populations, women with previously diagnosed gestational diabetes mellitus (GDM) are at particularly high risk of developing T2D. The success in reducing the occurrence of T2D among women with previous GDM could be achieved only if appropriate preventive measures are undertaken. According to the American Diabetes Association (ADA) and the Canadian Diabetes Association (CDA), lifestyle modifications aimed at reducing body weight and increasing physical activity are recommended and women are encouraged to be breastfeeding their infants. Certain factors have been suggested as determinants of behavioral practices in women with prior GDM including cognitive and environmental factors. A better understanding of these issues is essential for developing effective preventive strategies and possibly reducing the prevalence of T2D in the population.The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.
Trial information was received from ClinicalTrials.gov and was last updated in October 2016.
Information provided to ClinicalTrials.gov by Laval University.