Human Epididymis Protein 4 in Normal Menstruating Women
This trial is active, not recruiting.
|Condition||healthy premenopausal women|
|Sponsor||Women and Infants Hospital of Rhode Island|
|Start date||March 2011|
|End date||July 2014|
|Trial size||60 participants|
|Trial identifier||NCT01337999, 10-0127|
The purpose of this study is to determine if Human Epididymis Protein 4 (HE-4) levels vary during the menstrual cycles in ovulatory women. HE-4 is a sensitive serological marker that is elevated in certain ovarian and endometrial cancers and can aid in the diagnosis of these malignant conditions. In order to optimize the utility of HE4 as a tumor marker in premenopausal women, its expression in the normal menstrual cycle needs to be characterized. We hypothesize that HE-4 levels do not vary in the menstrual cycle.
|United States||No locations recruiting|
|Other countries||No locations recruiting|
time frame: 5 times during menstrual cycle
Female participants from 18 years up to 45 years old.
Inclusion Criteria: - women age 18-45 years old - regular menstrual cycles (every 25-35 days) - normal BMI (19-25) - no hormonal contraception in the two menstrual cycles prior to enrollment Exclusion Criteria: - pregnancy - pelvic mass
|Official title||Human Epididymis Protein 4 in Normal Menstruating Women|
|Principal investigator||Beth Plante, M.D.|
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