Factors Related to the Progression of Chronic Kidney Disease
This trial is active, not recruiting.
|Condition||chronic kidney disease|
|Sponsor||Ankara Education and Research Hospital|
|Start date||March 2008|
|End date||May 2011|
|Trial size||90 participants|
|Trial identifier||NCT01317173, NEPH001|
Chronic kidney disease is a progressive disorder that has been influenced with many factors. Most of the patients has altered Ca P metabolism and these dis orders are the contributing factors of the disease progression. It has been recently documented that FGF23 and Klotho are the key factors of PTH secretion Ca-P metabolism. This study aimed to evaluate the impact of Klotho and FGF23 on the progression of stage 3-4 chronic kidney disease.
Serum creatinin level rise more than 2 times
Serum creatinin level rise less than 2 times
Progression of kidney disease
time frame: continuous measurement of kidney functions 3 monthly for two years or until the outcome reached
Evaluation of Ca P metabolism
time frame: 3 monthly for two years or until the outcome reached
Male or female participants from 18 years up to 65 years old.
Inclusion Criteria: - Non-diabetic chronic kidney disease Exclusion Criteria: - Presence of DM - Actively using calcium based phosphorus binder of vitamin D
|Official title||The Impact of FGF23 and Klotho on Progression of Chronic Kidney Disease|
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