Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities
This trial is active, not recruiting.
|Condition||mrsa - methicillin resistant staphylococcus aureus infection|
|Sponsor||NorthShore University HealthSystem Research Institute|
|Start date||October 2010|
|End date||March 2013|
|Trial size||4200 participants|
|Trial identifier||NCT01302210, AHRQ 1R18HSO19968-01|
Our hypothesis for the DERAIL MRSA program is that one can safely remove the colonization risk from nearly all residents (patients) in a way that does not interfere with the desired life-style for persons in these facilities and thereby reduce the risk of infection and lower the cost of care by avoiding preventable disease.
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
To test the effectiveness of an admission testing and immediate decolonization of positive persons protocol for reducing MRSA colonization prevalence in long term care facilities (LTCF's)
time frame: 12 months and 24 months
To further develop an Infection Control Outreach Program designed to provide expert guidance on infectious disease prevention specific to LTCF's
time frame: 2 years
Male or female participants at least 18 years old.
Inclusion Criteria: - All patients in 18 LTCF nursing units randomly selected as intervention or control units Exclusion Criteria: - Patients that choose not to be included in the program
|Official title||Detection, Education, Research and Decolonization Without Isolation in Long-term Care to Control(DERAIL)MRSA|
|Principal investigator||Lance R Peterson, MD|
|Description||The primary endpoint will be measuring the reduction in MRSA colonization prevalence (rate) in the intervention arm as compared to the control arm. One secondary endpoint is to compare the rate of MRSA disease in the intervention and control arms. The other secondary endpoint is to determine the cost of MRSA screening and decolonization and compare it to the cost of MRSA disease treatment (both medication cost and the expense of any needed hospitalization for therapy of MRSA infection therapy) in the control arm. Achieving our primary goal of MRSA control will also demonstrate two secondary goals wthe investigators aim to achieve: one being that a scientific, planned approach to the issue of specific healthcare-associated infection in LTCFs can solve these problems and the other that a partnership between acute and long-term care is beneficial in dealing with patient safety and quality practices across the United Sates Healthcare continuum.|
Call for more information