PERSONALIZED ANTIDEPRESSANT ADHERENCE STRATEGIES FOR DEPRESSED ELDERS
This trial is active, not recruiting.
|Sponsor||Weill Medical College of Cornell University|
|Collaborator||National Institute of Mental Health (NIMH)|
|Start date||January 2011|
|End date||June 2016|
|Trial size||260 participants|
|Trial identifier||NCT01301859, 1R01MH087562-01A1|
The study is a randomized controlled trial to test the usefulness of a brief intervention to improve adherence to antidepressant medication prescribed to older adults in a primary care setting. Study will be conducted at Weill Cornell and University of Michigan.
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
|Masking||single blind (outcomes assessor)|
|Primary purpose||health services research|
Brief Medication Questionnaire
time frame: 12 week Follow up
Hamilton Depression Rating Scale
time frame: 12 weeks
Male or female participants at least 65 years old.
Inclusion Criteria: Age: 65 and older; Newly prescribed antidepressant medication by PCP (within past 10 days); Has not been prescribed antidepressant medication in previous 6 months. Exclusion Criteria: High suicide risk, i.e. intent or plan to attempt suicide Presence of alcohol abuse, substance abuse, psychotic disorder or, bipolar disorder as observed on the SCID, are excluded; Dementia: MMSE below 24, clinical assessment, or medication; Inability to speak English; Aphasia interfering with communication; Terminal illness or current chemotherapy
|Official title||Treatment Initiation and Participation Program (TIP)|
|Principal investigator||JoAnne Sirey, Ph.D.|
|Description||The intervention is a brief, psychosocial intervention designed to be an adjunct to pharmacotherapy prescribed by a primary care physician. It includes psychoeducation, problem solving and development of goals and a personalized adherence strategy. The intervention includes three 30 minute sessions during the first 6 weeks of treatment and a follow-up phone call two weeks later.|
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