Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity
This trial is active, not recruiting.
|Condition||acute compartment syndrome|
|Start date||January 2010|
|End date||December 2016|
|Trial size||63 participants|
|Trial identifier||NCT01283451, NIRS-01|
Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS). Placement of these sensor pads on the surface of the skin must be such that light penetrates the intended compartment without inadvertently obtaining measurements of an adjacent compartment. The objective of this study is to examine whether the NIRS measurements of each compartment truly represent the tissue perfusion of the intended compartment, as indicated by the predictable decrease in muscle oxygenation of a given compartment in response to muscle fatigue. The investigators hypothesize that the tissue oxygenation values of the stimulated compartment will significantly decrease following muscle stimulation, indicating that the intended muscle compartment was successfully isolated. Additionally, the investigators hypothesize that NIRS values of unstimulated muscle compartments will not change from baseline.
Near infrared spectroscopy
time frame: <30 minutes
Male or female participants from 18 years up to 75 years old.
- 18-75 years old
- no current extremity injuries
- willing to provide written informed consent
- history of any anatomy-altering surgery to the extremity in question
- history of peripheral vascular disease
- history of pulmonary disease
|Official title||Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity|
|Principal investigator||Michael Shuler, MD|
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