Intervention to Reduce Body Burdens of PCBs in Residents of Anniston, Alabama
This trial is active, not recruiting.
|Condition||body burden of potentially toxic lipophilic compounds|
|Collaborator||National Institute of Environmental Health Sciences (NIEHS)|
|Start date||December 2010|
|End date||April 2012|
|Trial size||28 participants|
|Trial identifier||NCT01261338, 10100801 1R21ES019206-01, 1R21ES019206-01|
Because of industrial pollution, a large number of people in Annison, Alabama, have elevated body burdens of the class of compounds known as polychlorinated biphenyls (PCBs). There is evidence that these compounds are associated with risks to health including diabetes. There is also evidence that the consumption of a non-absorbable dietary fat can reduce the level of compounds like PCBs. This clinical trial will test the hypothesis that a non-absorbable dietary fat can reduce the levels of PCBs in subjects in Anniston.
|Endpoint classification||pharmacokinetics study|
|Intervention model||parallel assignment|
|Masking||double blind (subject, investigator)|
|Primary purpose||basic science|
Rate of change of blood levels of PCBs.
time frame: one year
Male or female participants from 21 years up to 75 years old.
Inclusion Criteria: - Elevated blood level of PCBs Exclusion Criteria: - Pregnancy - Breast-feeding - Weight-loss medication - Gastrointestinal disease
|Official title||Intervention to Reduce Body Burdens of PCBs in Residents of Anniston, Alabama|
|Principal investigator||Ronald J Jandacek, Ph.D.|
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