This trial has been completed.

Conditions blood stream infections, mrsa infections
Treatment healthcare staff processes for infection prevention
Sponsor Maine Medical Center Research Institute
Collaborator Agency for Healthcare Research and Quality (AHRQ)
Start date July 2010
End date April 2012
Trial size 175 participants
Trial identifier NCT01255943, HHSA290200600013


The purpose of this study is to implement strategies for improved efficiency and waste reduction ("Toyota Lean") and positive deviance, a social behavioral change process, utilizing frontline healthcare personnel to reduce infection bloodstream infection and MRSA infection in outpatient dialysis care. In two outpatient dialysis units, dialysis unit healthcare staff will be educated in Toyota lean techniques and conduct periodic "discovery and action" dialogues to identify and implement care process changes to reduce infection. Outcomes to be monitored will include incidence of bloodstream infections and MRSA infections of all types. Data will be assessed at quarterly intervals using interrupted time series analysis.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model cohort
Time perspective prospective
These patients are observed in two outpatient dialysis units with a combined census of approximately 175 patients
healthcare staff processes for infection prevention
Toyota lean and positive deviance discovery and action dialogues to facilitate process improvement

Primary Outcomes

Incidence of bloodstream infections
time frame: 14 months

Secondary Outcomes

Incidence of MRSA infections
time frame: 14 months

Eligibility Criteria

All participants of any age.

Inclusion Criteria: all hemodialysis patients at two outpatient dialysis units Exclusion Criteria:peritoneal dialysis patients

Additional Information

Official title Testing Spread and Implementation of Novel MRSA-Reducing Practices
Principal investigator Mark G Parker, MD
Trial information was received from ClinicalTrials.gov and was last updated in March 2017.
Information provided to ClinicalTrials.gov by Maine Medical Center Research Institute.