This trial is active, not recruiting.

Conditions muscle strength, tendon elasticity, muscle csa, tendon csa, vdr receptor
Treatment 12 weeks strength exercise training
Sponsor Bispebjerg Hospital
Collaborator Institute of Sports Medicine, Copenhagen
Start date November 2010
End date February 2012
Trial size 40 participants
Trial identifier NCT01252381, BBH 77


The aim is to investigate the importance of vitamin D levels to achieve the effect of strength training. If we can show that vitamin D has an effect of training, the ultimate goal is to find out why and how vitamin D affects muscle.

This would potentially have important implications for public health. Since a large number of populations, including elderly, are shown to have too little vitamin D and also has low muscle strength, it will be essential that these people added vitamin D in relation to training and rehabilitation.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking double blind (subject, investigator)
(Active Comparator)
12 weeks strength exercise training
Training 3 times a week, leg extensions and leg press
(Placebo Comparator)
12 weeks strength exercise training
Training 3 times a week, leg extensions and leg press

Primary Outcomes

Cross-sectional area of thigh musculature and knee tendon
time frame: 12 weeks
VDR potential target CYP27b1
time frame: 12 weeks

Eligibility Criteria

Male participants from 20 years up to 75 years old.

Inclusion Criteria: - Men 20-30 or 60-75 years old Exclusion Criteria: - smokers Knee problems On medication affecting protein synthesis High exposure to sun light (ex. ski holiday) during the trial

Additional Information

Official title The Importance of Supplementary Intake of Vitamin D on the Efficacy of 12 Weeks of Strength Training in Both Vitamin D Sufficient Younger and Older People
Trial information was received from ClinicalTrials.gov and was last updated in February 2012.
Information provided to ClinicalTrials.gov by Bispebjerg Hospital.