Overview

This trial is active, not recruiting.

Condition inflammation
Treatments resveratrol, placebo comparator: sugar pill
Sponsor Marywood University
Start date November 2010
End date June 2011
Trial size 44 participants
Trial identifier NCT01244360, 2RESMU194218, MU Smoliga Resveratrol

Summary

The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification safety study
Intervention model parallel assignment
Masking double blind (subject, caregiver)
Primary purpose treatment
Arm
(Placebo Comparator)
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.
placebo comparator: sugar pill
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.
(Active Comparator)
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.
resveratrol
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

Primary Outcomes

Measure
Vascular function
time frame: 4 weeks, with option of additional 4 week treatment period

Secondary Outcomes

Measure
Body fat percentage
time frame: 4 weeks, with optional additional 4 week treatment period
inflammation biomarkers
time frame: 4 weeks, with optional additional 4 week treatment period
cognitive function
time frame: 4 weeks, with optional additional 4 week treatment period

Eligibility Criteria

Male or female participants from 45 years up to 75 years old.

Inclusion Criteria: - men and women between 45 and 75 years of age - Normal heart rate and Blood pressure - Ability to use personal computer interface - Successful completion of physical activity readiness questionnaire Exclusion Criteria: - Cardiovascular disease, uncontrolled hypertension, lung disease - inability to tolerate exercise - have taken grape related supplement in past 12 months - current use of drugs or dietary supplements to enhance exercise performance - allergy to wine, grape juice or grape seed supplements

Additional Information

Official title The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance
Principal investigator James Smoliga, Ph.D.
Description Measurements - blood laboratory parameters - cognitive assessment changes - body composition changes - vascular endothelial response
Trial information was received from ClinicalTrials.gov and was last updated in June 2011.
Information provided to ClinicalTrials.gov by Marywood University.