Isolation and Authentication of Mesenchymal Stem Cell-like Progenitor Cells From the Degenerated Intervertebral Disc of Lumbar Spine
This trial is active, not recruiting.
|Conditions||lower back pain, disc degeneration|
|Sponsor||Taipei Medical University WanFang Hospital|
|Start date||September 2010|
|End date||October 2011|
|Trial size||20 participants|
|Trial identifier||NCT01213953, 98025|
The study is designed for evaluating the presence of mesenchymal stem cells of vertebral disc. Isolation and authentication of these cells may be applied for the vertebral disc regeneration and the research tissue engineering.
Male or female participants at least 20 years old.
Inclusion Criteria: - The adults with disc degeneration（age >= 20 years old） A. Herniated intervertebral disc. B. Spondylolisthesis. C. Spondylolysis. D. Other causes of disc degeneration. Exclusion Criteria: - Age < 20 years old. - Pregnancy. - Spinal tumors. - Spinal infections.
|Official title||Isolation and Authentication of Mesenchymal Stem Cell-like Progenitor Cells From the Degenerated Intervertebral Disc of Lumbar Spine|
|Principal investigator||Hsieh-Hsing Lee|
|Description||We will collect the degenerative disc from adults and isolate the mesenchymal stem cell-like precursors cells. The function of osteogenic, chondrogenic, and lipogenic differentiation will be authenticated. The results will offer the information for cell source of tissue engineering in the future.|
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