This trial is active, not recruiting.

Conditions lower back pain, disc degeneration
Sponsor Taipei Medical University WanFang Hospital
Start date September 2010
End date October 2011
Trial size 20 participants
Trial identifier NCT01213953, 98025


The study is designed for evaluating the presence of mesenchymal stem cells of vertebral disc. Isolation and authentication of these cells may be applied for the vertebral disc regeneration and the research tissue engineering.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case-only
Time perspective prospective

Eligibility Criteria

Male or female participants at least 20 years old.

Inclusion Criteria: - The adults with disc degeneration(age >= 20 years old) A. Herniated intervertebral disc. B. Spondylolisthesis. C. Spondylolysis. D. Other causes of disc degeneration. Exclusion Criteria: - Age < 20 years old. - Pregnancy. - Spinal tumors. - Spinal infections.

Additional Information

Official title Isolation and Authentication of Mesenchymal Stem Cell-like Progenitor Cells From the Degenerated Intervertebral Disc of Lumbar Spine
Principal investigator Hsieh-Hsing Lee
Description We will collect the degenerative disc from adults and isolate the mesenchymal stem cell-like precursors cells. The function of osteogenic, chondrogenic, and lipogenic differentiation will be authenticated. The results will offer the information for cell source of tissue engineering in the future.
Trial information was received from ClinicalTrials.gov and was last updated in October 2010.
Information provided to ClinicalTrials.gov by Taipei Medical University WanFang Hospital.