The Effect of Whole Beans on Inflammation and Satiety
This trial is active, not recruiting.
|Treatments||couscous plus fiber, grape seed extract, whole beans|
|Sponsor||University of California, Davis|
|Start date||August 2010|
|End date||April 2012|
|Trial size||12 participants|
|Trial identifier||NCT01190384, 201018072|
Determine whether eating beans with a high fat meal will reduce the inflammatory response in people with the metabolic syndrome and increase feelings of satiety.
|Endpoint classification||efficacy study|
|Intervention model||crossover assignment|
|Masking||single blind (subject)|
|Primary purpose||basic science|
time frame: 6 hours
time frame: 48 hours
Male or female participants at least 21 years old.
Inclusion Criteria: Men and Women 21 years old and older with metabolic syndrome Exclusion Criteria: 1. Smokers 2. Female subjects who are pregnant or lactating 3. Subjects taking any medications that would interfere with outcomes of the study i.e. lipid lowering medications, anti-inflammatory drugs (i.e. ibuprofen), dietary supplements 4. Subjects with any known allergy or intolerance to foods involved in the study(cantaloupe, egg, dairy, wheat, beans, couscous, grape seed extract) 5. Subjects who are actively trying to lose weight 6. Subjects with unusual dietary habits (i.e. pica, anorexia nervosa, extreme food restriction, binging and/or purging disorders) 7. Subjects who are addicted to drugs or alcohol or who are <1 year recovery program 8. Subjects who present with significant psychiatric or neurological disturbances as determined by the primary investigator (i.e. uncontrolled bipolar disorder) These subjects will be referred to their primary care doctor for further care. 9. Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus (fasting blood sugar ≥126 mg/dl), uncontrolled hypertension (≥ 140/90mmHg), liver and kidney disease as identified by routine blood tests (chemistry panels). These subjects will be referred to their primary care doctor for further care.
|Official title||Bean Consumption: A Pilot Study in Overweight Men and Women on Immuno-metabolic and Food Intake Endpoints|
|Principal investigator||Chulani T Kappagoda, M.D., Ph.D.|
|Description||Determine whether eating beans with a high fat meal will reduce the inflammatory response in people with the metabolic syndrome; thereby possibly postponing the diagnosis of diabetes or other chronic inflammatory diseases. These researchers are also interested in how consuming beans can affect the length of time a person stays full after a meal.|
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