This trial is active, not recruiting.

Condition seborrheic keratosis
Treatments cryosurgery, curettage
Sponsor Milton S. Hershey Medical Center
Start date July 2010
End date October 2011
Trial size 30 participants
Trial identifier NCT01159860, IRB Protocol No. 33895


Seborrheic keratoses (SK's) are very common, but harmless skin lesions that commonly appear during adult life. Patients with seborrheic keratoses frequently desire treatment due to symptoms of itching and irritation or for cosmetic purposes. Seborrheic keratoses can be easily removed and have been treated in a number of different ways. Two of the simplest and most successful ways to remove seborrheic keratoses are cryosurgery and curettage.

The investigators are conducting this study to see which of these two treatments has the best result.

Approximately 24-30 people will take part in this research study at the Hershey Medical Center.

United States No locations recruiting
Other countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model factorial assignment
Masking single blind (investigator)
Primary purpose treatment
(Active Comparator)
One lesion on the patients' trunk or proximal extremities will be treated with cryosurgery.
freezing of lesion with liquid nitrogen
(Active Comparator)
One lesion on one side of the patients' trunk or proximal extremities will be treated by curettage.
the lesion will be anesthetized and destroyed with a curette.

Primary Outcomes

Partial or complete resolution of treated lesion.
time frame: 6 weeks

Eligibility Criteria

Male or female participants from 18 years up to 75 years old.

Inclusion Criteria: - have at least 1 seborrheic keratosis on each side of his/her trunk or proximal extremities. - be able to understand the consent form and evaluation of treatment questionnaire. Exclusion Criteria: - Children <18 are excluded from this study based on their inability to independently complete the informed consent and research associated questionnaire.

Additional Information

Official title Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?
Principal investigator Lance D. Wood, M.D.
Trial information was received from ClinicalTrials.gov and was last updated in August 2011.
Information provided to ClinicalTrials.gov by Milton S. Hershey Medical Center.