This trial is active, not recruiting.

Condition heroin dependence
Treatments cognitive behavioral therapy, methadone maintenance treatment
Sponsor Shanghai Mental Health Center
Start date April 2010
End date June 2011
Trial size 240 participants
Trial identifier NCT01144390, ShanghaiMHC


The purpose of this study is to explore barriers and determine whether optimizing protocol is effective in the treatment of heroin dependence in community-based MMT clinics.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking single blind (outcomes assessor)
Primary purpose treatment
cognitive behavioral therapy for heroin addicts with methadone maintenance treatment
cognitive behavioral therapy
cognitive behavioral therapy, one session per week and psycho-education lecture in group once per month
methadone maintenance treatment
methadone maintenance treatment
(Active Comparator)
methadone maintenance treatment for heroin addicts
methadone maintenance treatment
methadone maintenance treatment

Primary Outcomes

treatment retention
time frame: 12 months

Secondary Outcomes

in-treatment performance.
time frame: 12 months

Eligibility Criteria

Male or female participants from 18 years up to 65 years old.

Inclusion Criteria: - clinical diagnosis of heroin dependence - must be able to take methadone Exclusion Criteria: - schizophrenia and mood disorder - physical disabilities who could not come to take part in psychotherapy sessions.

Additional Information

Official title Barriers and Effect of Optimizing Intervention Protocols for Heroin Dependence in Community-based Methadone Maintenance Treatment (MMT): a Cohort Study
Principal investigator min ZHAO, Ph.D.
Description Drug dependence is one of the most serious public health problems worldwide. In China, among more than 100, 0000 registered drug addicts mostly are heroin dependence. Drug dependence post great risks to physical condition, their family and society, and can lead to infectious disease transmission. Though almost 500 MMT clinics which can offer MMT service to heroin addicts have been set up, there are still some problems, for example, poor compliance, high rate of dropping out and relapse which affect the service delivery to them. The guideline developed by WHO focused on psychotherapy to opiate addicts with MMT. So delivery of a set of comprehensive, integrated psychotherapy to opiate addicts is very critical in such methadone clinics.
Trial information was received from ClinicalTrials.gov and was last updated in March 2011.
Information provided to ClinicalTrials.gov by Shanghai Mental Health Center.