Overview

This trial is active, not recruiting.

Condition respiratory tract infections
Treatments experimental: training to antibiotic prescription, no education on antibiotic prescription rules.
Sponsor Henri Mondor University Hospital
Start date September 2004
End date April 2009
Trial size 170 participants
Trial identifier NCT01107223, PAAIR2

Summary

Respiratory tract infections are the most common indication for antibiotic prescribing in primary care. Several studies have shown a strong relationship between antibiotic use and bacterial resistance. The aim of this trial was to assess the long-term effect of a continuous education program on general practitioners antibiotic prescribing behaviour. 170 physicians were included in this study. Physicians randomized in the education group attended a two days seminar focused on evidence-based guidelines on antibiotic use in respiratory tract infections. The intervention was limited at physicians level and did not target the patients.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Intervention model parallel assignment
Masking open label
Primary purpose health services research
Arm
(Experimental)
Physicians randomized in the education group attended a two days seminar focussed on evidence-based guidelines on antibiotic use in respiratory tract infections.
experimental: training to antibiotic prescription
GPs assigned to the intervention group attended a two days didactic educational meeting on evidence-based guidelines for diagnosis and treatment of acute respiratory tract infection.
(Placebo Comparator)
no education on antibiotic prescription rules.
GPs assigned to control group received no specific recommendations on antibiotic prescription.

Primary Outcomes

Measure
Change in the percentage of prescriptions containing an antibiotic between control and intervention groups (seminar on the treatment of respiratory tract infections).
time frame: Effect of the intervention 4 to 6 months after the educational training.
Change in the cost of antibiotic prescription between control and intervention groups (seminar on the treatment of respiratory tract infections).
time frame: Effect of the intervention 4 to 6 months after the educational training.

Secondary Outcomes

Measure
Long term antibiotic prescription rates
time frame: Effect of the intervention 28 to 30 months after the educational training.
Long term antibiotic cost.
time frame: Effect of the intervention 28 to 30 months after the educational training.
Symptomatic drug prescription rates
time frame: Effect of the intervention 28 to 30 months after the educational training.
Symptomatic drug cost.
time frame: Effect of the intervention 28 to 30 months after the educational training.
Effect of patient age.
time frame: Effect of the intervention 28 to 30 months after the educational training.
Effect of a seminar on problem-solving strategy on prescriptions.
time frame: Effect of the intervention 28 to 30 months after the educational training.

Eligibility Criteria

Male or female participants of any age.

Inclusion Criteria: - General practitioners practicing in three departments of the Parisian area in France - General practitioners attending a two days didactic educational meeting on evidence-based guidelines for diagnosis and treatment of acute respiratory tract infection. Exclusion Criteria: - None

Additional Information

Official title Long Term Effect of General Practitioner Education on Antibiotic Prescribing: a Large Scale Randomized Study
Principal investigator Clause Attali, MD
Trial information was received from ClinicalTrials.gov and was last updated in April 2010.
Information provided to ClinicalTrials.gov by Henri Mondor University Hospital.