Exercise Training Effects in Patients With Heart Failure
This trial is active, not recruiting.
|Condition||chronic heart failure|
|Sponsor||University of Athens|
|Start date||November 2004|
|End date||April 2010|
|Trial size||40 participants|
|Trial identifier||NCT01071629, UOA-2010|
Chronic heart failure (CHF) is a common syndrome characterized by several central hemodynamic and peripheral vascular and muscle abnormalities including autonomic imbalance, neuro-hormonal over-activation and decreased oxidative status.
In patients suffering from CHF, exercise confers several beneficial effects on the cardiovascular and peripheral systems, mainly by continuous aerobic training. However, interval aerobic training has also been validated as an alternate form of training that increases the exercise capacity of patients who are in CHF.
Recent studies have suggested that resistance training alone or as a complementary program besides the traditionally aerobic continuous training might exert favorable effects. However, little it is known about the combined effects of interval and strength training in CHF patients.
Aim of this prospective randomized controlled study was to investigate the effects of combined interval and strength training comparing to interval training alone in CHF patients.
|United States||No locations recruiting|
|Other Countries||No locations recruiting|
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
Aerobic exercise capacity
time frame: 3 months
Endothelial function, oxygen kinetics, ventilatory drive
time frame: 3 months
Male or female participants from 18 years up to 80 years old.
Inclusion Criteria: - Stable systolic heart failure - NYHA functional class ≤ III - Optimal medical treatment Exclusion Criteria: - Contraindications for a maximal cardiopulmonary exercise testing (CPET) according to the American Thoracic Society/American College of Chest Physicians Statement - Moderate to severe COPD
|Official title||Aerobic Interval Training Versus Combined Aerobic Interval Training and Strength Training Effects in Patients With Heart Failure|
|Principal investigator||Serafim Nanas, MD|
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