Comparison of Visual Fields: Humphrey Field Analyzer (HFA) SITA Strategy, SCOPE (GATE Strategy) and Humphrey MATRIX Perimeter
This trial is active, not recruiting.
|Treatment||three different perimeters: hfa, octopus, matrix|
|Sponsor||University Hospital Tuebingen|
|Start date||November 2008|
|End date||December 2013|
|Trial size||30 participants|
|Trial identifier||NCT01068938, 116MIR08023, 428/2008BO1, X-SCOPE|
The purpose of this study is to compare three perimetric techniques regarding progression of the visual field.
risk of progression, Latanoprost monotherapy
time frame: 6 month
Male or female participants from 18 years up to 99 years old.
Inclusion Criteria: - max. ± 8 dpt sph, max. ± 3 dpt cyl - distant visual acuity > 10/20 - isocoria, pupil diameter > 3 mm - at least one risk of progression: optic disc (splinter) hemorrhage / cup to disc ratio (CDR) > 0.7 / inter-eye asymmetry of CDR >0.2 / notching of the optic disc /retinal nerve fibre layer (RNFL) defects / intraocular pressure( IOP) >22 mmHg / central corneal thickness < 520 µm / advanced visual field defect stage Aulhorn III / elder than 70 years Exclusion Criteria: - pregnancy, nursing - diabetic retinopathy - asthma - HIV+ or AIDS - history of epilepsy or significant psychiatric disease - medications known to effect visual field sensitivity - infections (e.g. keratitis, conjunctivitis, uveitis) - severe dry eyes - miotic drug - amblyopia - squint - nystagmus - albinism - any ocular pathology, in either eye, that may interfere with the ability to obtain visual fields,disc imaging or accurate IOP readings - keratoconus - intraocular surgery (except for uncomplicated cataract surgery) performed < 3 month prior to screening - history or signs of any visual pathway affection other than glaucoma - allergies with regard to topic glaucoma medication - history or presence of macular disease and / or macular edema - ocular trauma - medications known to affect visual field sensitivity
|Official title||Detection of Visual Field Defects and Scotoma Progression in Glaucomatous Optic Neuropathy, Using Short-term Intervals With Automated Scotoma-oriented Perimetry (SCOPE) and the Fast Thresholding Strategy GATE (German Adaptive Threshold Estimation)|
|Principal investigator||Ulrich Schiefer, MD|
Call for more information