The Genetics of Chiari Type I Malformation
This trial is active, not recruiting.
|Condition||chiari type i malformation|
|Start date||June 2009|
|End date||August 2020|
|Trial size||2000 participants|
|Trial identifier||NCT01060800, Pro00011231|
Duke University Medical Center is investigating the hereditary basis of Chiari type I malformations with or without syringomyelia (CM1/S). Our research is aimed at learning if CM1/S is indeed caused by factors inherited through the family and, if so, which genes are involved.
Genetic factors contributing to Chiari Type I malformation
time frame: end of study
Male or female participants of any age.
- Families who have TWO OR MORE family members with Chiari Type I Malformation, with or without syringomyelia. These family members must be related to each other by blood, and BOTH must be willing to participate.
- Singleton cases of Chiari Type I Malformation
- Presence of supratentorial or infratentorial tumors
- Presence of a lumbar shunt
- History of birth trauma
- History of spina bifida
- History of cervical or cranial surgery unrelated to CM1
|Official title||The Genetics of Chiari Type I Malformation (CMI) With or Without Syringomyelia|
|Principal investigator||Allison Ashley-Koch, PhD|
|Description||Duke University Medical Center is actively recruiting families who have TWO OR MORE family members with Chiari Type I Malformations, with or without syringomyelia. These family members must be related to each other by blood, and BOTH must be willing to participate.|
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