Mindfulness Based Cognitive Therapy for Recurrent Depression
This trial is active, not recruiting.
|Condition||depressive disorder, major|
|Treatment||mindfulness based cognitive therapy|
|Collaborator||Fonds Psychische Gezondheid|
|Start date||January 2005|
|End date||March 2010|
|Trial size||338 participants|
|Trial identifier||NCT01038765, 2005 6028, MFN-2005-2010|
The purpose of this study is to investigate the effectiveness and possible mediating factors of Mindfulness Based Cognitive Therapy (MBCT) for recurrent depression.
|Endpoint classification||efficacy study|
|Intervention model||parallel assignment|
Mindfulness Based Cognitive Therapy
3-month waiting list group
Relapse/Recurrence of Major Depressive Episode
time frame: 6, 9, 12, 15 months
Psychiatric symptoms and mindfulness skills measured by questionnaires
time frame: 0, 3, 6, 9, 12, 15 months
Male or female participants at least 18 years old.
Inclusion Criteria: - 3 or more previous depressive episodes - if treated with medication: constant dose of at least 6 weeks Exclusion Criteria: - Bipolar Disorder - Psychotic disorder - Neurological or somatic illness affecting depression or outcome measures - Current alcohol or drugs dependency - Acute need of psychiatric treatment
|Official title||Mindfulness Based Cognitive Therapy for Patients With Recurrent Depression: a Clinical Trial|
|Principal investigator||Anne EM Speckens, Prof. dr.|
|Description||Mindfulness Based Cognitive Therapy (MBCT) is a 8 session group intervention and is well described by several authors. Previous studies showed Mindfulness Based Cognitive Therapy (MBCT) to be effective to prevent relapse in patients with recurrent depression and 3 or more previous depressive episodes. Study aims are: 1. to replicate previous findings in The Netherlands, by a research team which did not develop the intervention 2. to investigate if MBCT is applicable for patients with recurrent depression and current depressive symptoms 3. to examine possible mediators of treatment effect and predictors of relapse in the year following the treatment In this study, patients are randomly assigned to a MBCT intervention group or a waiting list control group. Patients allocated to the waiting list control condition will receive the MBCT course three months later. All patients who participated in a MBCT training will be assessed during the year following the completion of the MBCT course. We aim to include about 220 patients.|
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