Overview

This trial is active, not recruiting.

Condition cardiopulmonary arrest outcome
Sponsor Shaare Zedek Medical Center
Start date March 2009
End date September 2017
Trial size 1600 participants
Trial identifier NCT00998140, NIHPR 08/90/a

Summary

Resuscitative efforts have been shown to be unsuccessful in most cases of out-of-hospital cardiac arrest (OHCA), and survivors who do recover cardiac function often sustain severe hypoxic brain damage. Time to efficacious care is a primary determinant of disability-free survival. In the Jerusalem district, only 9% of OHCA patients present with ventricular tachycardia/ventricular fibrillation (VT/VF) as the primary rhythm, whereas 77% present with asystole; this seems primarily to be the result of long collapse-to-arrival times. Nevertheless, overly zealous resuscitation is undertaken in a high proportion of arrests with a futile prognosis, leading to excessive costs.

Study hypotheses:

1. Subpopulations for whom intervention is futile/counter-productive are identifiable

2. Substantial waste of resources can be avoided

3. Optimization of emergency medical services (EMS) reorganization without adding resources is an achievable goal

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model cohort

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - All victims of non-traumatic out-of hospital cardiopulmonary arrest (defined as the absence of either spontaneous respiration or palpable pulse or both) within the Jerusalem district. Exclusion Criteria: - Patients with do-not-resuscitate orders or an advance directive to that effect.

Additional Information

Official title Optimizing Resuscitation After Cardiac Arrest in the Community: Increasing the Probability of Survival While Reducing Costs
Principal investigator Sharon Einav, MD
Trial information was received from ClinicalTrials.gov and was last updated in April 2016.
Information provided to ClinicalTrials.gov by Shaare Zedek Medical Center.