Overview

This trial is active, not recruiting.

Conditions spatial neglect, deficits in attention motor control and perception
Treatment prism adaptation treatment
Sponsor Kessler Foundation
Collaborator U.S. Department of Education
Start date October 2012
End date December 2017
Trial size 160 participants
Trial identifier NCT00989430, AMBarrett3, Spatial Neglect

Summary

The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke.

This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Allocation randomized
Endpoint classification efficacy study
Intervention model parallel assignment
Masking open label
Primary purpose treatment
Arm
(Experimental)
Two weeks of prism adaptation treatment followed by 4 weekly assessments and long-term follow-ups at the 3rd and 6th months.
prism adaptation treatment
Wearing prism goggles and performing visuomotor tasks during therapy sessions.
(No Intervention)
Participants will continue with their standard inpatient rehabilitation care. They will be assessed with cognitive and functional scales for tracking their recovery.

Primary Outcomes

Measure
Improvement in Spatial Neglect
time frame: 6 months

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - The subject is 18 to 100 years of age, inclusive. - The subject has had a stroke on the right side of the brain. - The subject is able to give Informed consent. - The subject has a spatial neglect (if known). - The subject is able and willing to comply with the study protocol, including availability for all scheduled clinic visits. Exclusion Criteria: - The subject has or had a serious brain condition other than stroke.

Additional Information

Official title Prism Adaptation Therapy for Spatial Neglect: Theoretical and Practical Outcomes
Principal investigator Anna M Barrett, MD
Description The purpose of this research study with a randomized controlled design is to examine the effects of prism adaptation treatment on two visual-spatial recovery components. After a stroke, an "internal GPS", locating where objects or people lie in a particular area of space, may be impaired. Alternately, a stroke may impair precise visual-spatial hand and body aiming movements. The research team wishes to discover whether prism adaptation treatment (two weeks of daily 20-min sessions of goal-directed movement with prism goggles) affects visual-spatial where or aiming errors selectively after stroke. This research represents one of the first attempts to apply what we know about the brain from neuroscience research, to modern clinical rehabilitation practices.
Trial information was received from ClinicalTrials.gov and was last updated in February 2016.
Information provided to ClinicalTrials.gov by Kessler Foundation.