Overview

This trial is active, not recruiting.

Conditions lung cancer, neoplasms, lung
Treatment propofol, remifentanil, sevoflurane
Sponsor Asan Medical Center
Start date October 2007
End date June 2009
Trial size 400 participants
Trial identifier NCT00935571, 20090708

Summary

The purpose of this study is to evaluate the incidence of postthoracotomy pain between total intravenous anesthesia (TIVA)and inhalation anesthesia after lung surgery.

United States No locations recruiting
Other Countries No locations recruiting

Study Design

Observational model case control
Time perspective prospective
Arm
Group I: anesthetized with TIVA (Propofol + Remifentanil) Group II: anesthetized with inhalation (sevoflurane)
propofol, remifentanil, sevoflurane diprivan
Propofol: using target controlled infusion (TCI); 1-3ug/ml remifentanil: using TCI by 5-20 ng/ml sevoflurane: 2-3volume% (1-2 MAC)

Primary Outcomes

Measure
Incidence of pain
time frame: 3 and 6 months later after operation

Secondary Outcomes

Measure
pain characters
time frame: 3 and 6 months later after operation

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - patients undergo elective thoracotomy of lung surgery Exclusion Criteria: - emergency operation age under 18 years patients with unstable hemodynamics

Additional Information

Official title Incidence of Postthoracotomy Pain Following General Anesthesia: A Comparison Between TIVA and Inhalation Anesthesia
Description Thoracotomy is one of the most painful surgical incisions. It has been shown that 5-80% of patients still suffer from thoracic pain 2-3 months after surgery and the international association for the study of pain (IASP) defines postthoracotomy pain syndrome (PTTS)as pain that recurs or persists at least 2 months after surgical procedure. Previous reports have shown that the incidence of PTTS varies according to preoperative pain, pain intensity, sex, and types of procedure. However, little is known about the effect of the type of anesthesia to postthoracotomy pain.
Trial information was received from ClinicalTrials.gov and was last updated in July 2009.
Information provided to ClinicalTrials.gov by Asan Medical Center.