This trial is active, not recruiting.

Condition stroke
Sponsor University of Cincinnati
Collaborator National Institute of Neurological Disorders and Stroke (NINDS)
Start date July 2008
End date June 2021
Trial size 1260 participants
Trial identifier NCT00930280, 36695-3, NS036695-10A2


The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH).

United States No locations recruiting
Other countries No locations recruiting

Study Design

Observational model case control
Time perspective prospective
People who have had a hemorrhagic stroke, specifically an intracerebral hemorrhage, and live within a 100 mile radius of the University of Cincinnati.
Healthy volunteers who are randomly identified in the same 100 mile radius of the University of Cincinnati and have not had a hemorrhagic stroke.

Primary Outcomes

The analysis of the presence of specific genetic markers associated with hemorrhagic stroke versus the control group.
time frame: Ongoing to be completed at the end of June 2013.

Secondary Outcomes

Analysis of risk factors such as age, race, gender, current smoking, heavy alcohol use, use of anticoagulants, diabetes, hemorrhagic stroke family history, hypertension, etc. in people with hemorrhagic stroke versus the control group.
time frame: Ongoing to be completed at the end of June 2013.

Eligibility Criteria

Male or female participants at least 18 years old.

Inclusion Criteria: - Age 18 years or older - Resident (6 months or longer) within 100 miles of University of Cincinnati. - Fulfillment of the criteria for spontaneous ICH - No evidence of trauma, brain tumor/metastases, hemorrhagic transformation of ischemic stroke or infectious processes as a cause of the hemorrhage. - Ability of the patient or legal representative to provide consent for an interview, blood pressure determinations and DNA sampling. Exclusion Criteria:

Additional Information

Official title Genetic and Environmental Risk Factors for Hemorrhagic Stroke
Principal investigator Daniel Woo, M.D.
Trial information was received from ClinicalTrials.gov and was last updated in December 2015.
Information provided to ClinicalTrials.gov by University of Cincinnati.