Methadone in Pediatric Anesthesia
This trial is active, not recruiting.
|Sponsor||Washington University School of Medicine|
|Start date||May 2009|
|End date||May 2017|
|Trial size||31 participants|
|Trial identifier||NCT00921843, 08-1195|
This study will determine the pharmacokinetics of intravenous (IV) methadone in children undergoing surgery.
|Endpoint classification||efficacy study|
|Intervention model||single group assignment|
Methadone administration 0.1mg/kg, 0.2mg/kg or 0.3 mg/kg
Determine PKs of IV methadone in children undergoing surgery
time frame: 1 year
Male or female participants from 5 years up to 18 years old.
Inclusion Criteria: - Age 5-18 - Undergoing General anesthesia and surgery with anticipated postoperative inpatient stay of greater than or equal to 3 days - Signed, written, informed consent from legal guardians and assent from patient Exclusion Criteria: - History of or known liver or kidney disease
|Official title||Methadone in Pediatric Anesthesia|
|Principal investigator||Evan Kharasch, MD, PhD|
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